Weight loss surgery may lower risk of Alzheimer's in the diabetic's (HealthDay)

while the finding is not conclusive, suggests a new study that weight loss surgery in obese diabetics could reduce the risk of developing Alzheimer's disease.

Researchers found that gastric bypass, when tested six months after their weight-loss operations, less expression of genes that thought had patients, precursor of the debris that the brains of people with Alzheimer's disease be plugged.

"Our study for the first time shows, that weight loss from bariatric surgery leads to a decrease in the expression of genes associated with Alzheimer's disease," said study author Dr. Paresh Dandona, Professor at the State University of New York at Buffalo, in a press release of the endocrine society.

The study was planned Sunday be presented the annual meeting of the society in Boston. Research meetings should be considered as preliminary, because it not the same control as studies subjected was published in the most medical journals.

The study analyzed the blood of 15 patients with type 2 diabetes researchers, the weight loss surgery went through and lost an average of about 86 pounds more than six months. In comparison to before the operation, which expression of amyloid precursor protein patients fell by 22 per cent, and also noticed the researchers less expression of other genes that seem to be associated with Alzheimer's disease.

However check the patients for signs of the disease not the study, so there is no way to know whether their actually went risk.

Scientists believe is there a link between obesity and diabetes, which are displayed is to increase the risk of Alzheimer's Associate Director of the Alzheimer's Disease Center at the University of California, said Greg Cole, Los Angeles. He said obesity may boost inflammation in the body and brain.

"Weight loss is expected to improve health, but a disadvantage is that the epidemiology of weight loss is complicated," he added. "A harbinger of incipient dementia can weight loss in the elderly." Further, each after a National Institute on aging study, there may be significant differences in the way in which changes weight the risk for Alzheimer's influence in the middle of life: women who seem to lose between 30 and 45 weight to be actually vulnerable. "

More information

Visit for more information about Alzheimer's disease of the U.S. National Library of medicine.

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